A Short Study on the Success of the Gene Ontology

Michael Bada, Robert Stevens, Carole Goble, Yolanda Gil, Michael Ashburner, Judith A. Blake, J. Michael Cherry, Midori Harris, Suzanna Lewis


While most ontologies have been used only by the groups who created them and for their initially defined purposes, the Gene Ontology (GO), an evolving structured controlled vocabulary of nearly 16,000 terms in the domain of biological functionality, has been widely used for annotation of biological-database entries and in biomedical research. As a set of learned lessons offered to other ontology developers, we list and briefly discuss the characteristics of GO that we believe are most responsible for its success: community involvement; clear goals; limited scope; simple, intuitive structure; continuous evolution; active curation; and early use.

Full Text: PDF
Type of Paper: Ontology Paper
Keywords: Gene Ontology; ontology development; biological database; annotation
Show BibTex format: BibTeX